This article is part of our Yahoo DFS Soccer series.
For detailed odds and stats, check out the Fantasy Champions League: Wednesday Cheat Sheet.
3:00 p.m: Atletico Madrid v. Club Brugge
3:00 p.m: PSV Eindoven v. Inter Milan
3:00 p.m: Borussia Dortmund v. Monaco
3:00 p.m: Tottenham v. Barcelona
3:00 p.m: Napoli v. Liverpool
3:00 p.m: Porto v. Galatasaray
Lionel Messi, BAR at TOT (€27): Messi lit up PSV with a hat trick en route to 40 points in his UCL opener, and while the matchup at Tottenham presents a bigger challenge, Messi is one of few players in the world who are truly matchup proof. He's scored or assisted in six of eight games to start the season, and with Spurs having conceded two goals in each of their last two home games, Messi stands a good chance to be involved on the scoresheet.
Antoine Griezmann, ATM v. CLUB (€25): Griezmann has nearly the same anytime goal scorer odds as Messi but has a much easier matchup at home against Club Brugge. Griezmann has scored or assisted in all three home appearances this season, and given what's at stake with Atletico looking to position themselves at the top of Group A, we can expect him to continue to be involved.
Hirving Lozano, PSV v. INT (€15):Lozano's five goals through seven games are level with Luuk de Jong (€16) and Gaston Pereiro (€14) for the team lead, but it's Lozano who checks in with the best goal scorer odds on the squad.